The amount of basic research on stem cells has grown almost exponentially, and some clinical trials are underway. While most of the public has been fairly well informed about the controversial but seemingly endless (and sometimes overhyped) potential of embryonic stem cells, insight into the surprising level of activity of adult stem cells in the body and their therapeutic possibilities is less well known.
Stem cells can be described as being healthy young recruits into the Army who have completed the basic training phase of their careers, but who are as yet unassigned to any military specialty school, from which they could graduate, and obtain promotion.
But as in the Army, there are a small number of recruits who languish unassigned, and after a while they are deemed irrelevant, because it is thought that whatever their potential was, it had been wasted through lack of use. It is often thought that it is better for the Army ----and the human body in times when it is in peril of some disease, injury, or in aging---- to bring in altogether new recruits, and to ignore the old ones that were somehow left unassigned.
And such has been the emphasis in stem cell research: Focus on the embryonic ones; underestimate the prospects of the ones that have been in the Army for a long time, but seemingly have not been specially trained or deployed anywhere notably .
WHERE TO FIND WORKING ADULT STEM CELLS? TRY YOUR SKIN & HAIR!
For a long time it was thought that, at least in humans, adults had relatively few stem cells, in a few locations, and they did not seem to do much. They were generally thought of as relicts left over from the active growing processes of ourselves as we developed from embryos to fetuses to infants.
Part of this view resulted from a failure to see that a variety of seemingly specialized “ body repair tissues”, thought of only in the context of their particular organs systems and in therapies related to them, were in fact, actually stem cells.
One of the greatest failures of the public imagination and perhaps of science reporting has been to realize that bone marrow transplants, procedures now done for decades, involve what amounts to stem cells.
But this is scarcely the only example of adult stem cells that has been staring us in the face.
Consider the hair follicle, one of the subjects of an important review in a recent issue of Science (Li and Clevers 2010).
They report that it was not until 2004 that Blainpain et al were able to demonstrate that the hair follicles and surrounding skin not only contained stem cells, but in fact two different types: the quiescent (the kind of seemingly indolent stem cell we expect to find in adults) in the bulge area of the hair follicle, and rather active ones that self-renew their population (in other words, they don’t just sit there, they also provide for their replacement as undifferentiated cells, before they begin the process of turning themselves into whatever specialized replacement cell is needed, in other words, when they enter the TA (Transit Amplifying) stage.
Most of the time, this surprising transformation works remarkably well, but the flip side is evident when this remarkable self-renewal of undifferentiated cells goes awry.
This seems to be the case with the some of the most common (and unfortunately most deadly if untreated) skin cancers melanomas (Cook and Sturm 2008). Their best guess is that beneficial recruitment for skin (and presumably hair) replacement goes bad when a family of cell transcription factors known as POU malfunctions. Not all POU factors are bad, by any means, but the wrong one, or the right one in the wrong place, seems to spell the difference. Marhaba et al (2008) suggest that even adult stem cells that get into a bad neighborhood tend to fall in with a bad crowd: stem cells turn into cancer-initiating cells.
ARE EMBRYONIC CELLS STEM THERAPIES FOR THE HEART LIKELY TO BE THE ONLY WAY TO GO?
There has been significant research on heart attack repair in adult laboratory animals (rats, actually) using human embryonic stem cells (LaFlamme et al 2007), and general discussion of its use on humans (Leor et al 2007) continues. But in a recent review by Passier, van Laake and Mummery (2008), it is pointed out that as far back as 2003 Beltrami et al (2003) demonstrated that while the adult heart is overwhelmingly composed of terminally specialized cells, repair after heart attacks involves a residual population of the body’s own adult stem cells.
The preponderance of stem cell studies in connection with heart attack (and stroke) repair is actually with adult bone marrow lines (see for example, Cesari et al 2010, Edelberg and Ballard, 2008), with mixed, but generally favorable results Gersh et al (2009), but that the injection of reprogrammed adult fibroblasts (cells involved in connective tissue, usually obtained from skin snippets) that are treated to become “plenipotentiary” is probably the most exciting (and least controversial) way to go among many competing approaches.
One possible reason is that while it has not been commonly detected in human trials, a paradoxical outcome seen in animals of bone marrow transplantation to induce heart attack repair may be good heart repair but increased atherosclerosis (Hristov et al 2008).
OTHER ORGANS, OTHER POSSIBILITES
Quite possibly the two other organ system most involved in stem cell based research are those related to diabetes, and to brain and spinal cord repair.
The pancreas contains two types of cells related to glucose regulation and digestion. By far, the greatest interest has been in the beta cells whose absence or poor function is the cause of diabetes. While, based on fundamental studies of the embryonic development of the pancreas, Scharfmann et al (2008) likely represent the majority view that embryonic stem cells hold the greatest promise to enhance the production and performance of these beta cells, Bayens and Bouwens (2008) suggest that pancreatic cells of the other type ----acinar cells----derived from adult cadavers can be reprogrammed into becoming, or at least functioning, like stem cells that will turn into beta cells.
Probably the most overpromised, under-documented, and downright shady practice of stem cell therapy of either embryonic or adult type is done in connection with neurological disorders. Carroll and Borlongan (2008) describe the appalling claims and practices of “stem cell tourist” hotspots that have some bases of operation in the People’s Republic of China, the Carribean, and Eastern Europe. But they also describe their own painstaking progress in the area of using adult stem cells in rodent models, including the surprising finding that a successful experimental therapy that used direct injection into the brain, was actually replicated by using intravenous adult stem cell transplantation.
More work, of course, needs to be done. More work will inevitably be done. But perhaps most intriguingly of all, more of it will involve adult stem cells and their reprogrammed adult cell analogues, than was imagined even a decade ago, when the promise of embryonic stem cells first held our (except for ethical issues) undivided attention.
Tony Stankus, FSLA [email protected] Life Sciences Librarian, Science Coordinator & Professor
University of Arkansas Libraries MULN 223 E
365 North McIlroy Avenue
Fayetteville AR 72701-4002
Voice: 479-575-4031
Fax: 479-575-4592
Baeyens, L., and L. Bouwens. 2008. Can beta-cells be derived from exocrine pancreas? Diabetes, Obesity & Metabolism 10 Suppl 4, (11): 170-8.
Beltrami, Antonio P, Laura Barlucchi, Daniele Torella, Mathue Baker, Federica Limana, Stefano Chimenti, Hideko Kasahara, et al. 2003. "Adult cardiac stem cells are multipotent and support myocardial regeneration." Cell 114 (6): 763-776.
Blanpain, Cedric, William E Lowry, Andrea Geoghegan, Lisa Polak, and Elaine Fuchs. 2004. "Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche." Cell 118, (5) : 635-648.
Carroll, James E., and Cesar V. Borlongan. 2008. Adult stem cell therapy for acute brain injury in children. CNS & Neurological Disorders Drug Targets 7, (4) (10): 361-9.
Cesari, Francesca, Patrizia Nencini, Mascia Nesi, Roberto Caporale, Betti Giusti, Rosanna Abbate, Anna Maria Gori, and Domenico Inzitari. 2009. Bone marrow-derived progenitor cells in the early phase of ischemic stroke: Relation with stroke severity and discharge outcome. Journal of Cerebral Blood Flow and Metabolism 29, (12) 1983-90.
Edelberg, Jay M., and Victoria L. T. Ballard. 2008. Stem cell review series: Regulating highly potent stem cells in aging: Environmental influences on plasticity. Aging Cell 7, (4) (08): 599-604.
Elabd, Christian, Chiara Chiellini, Mamen Carmona, Jean Galitzky, Olivia Cochet, Rasmus Petersen, Luc Pénicaud, et al. 2009. Human multipotent adipose-derived stem cells differentiate into functional brown adipocytes. Stem Cells 27, (11): 2753-60.
Gering, Martin, and Roger Patient. 2010. Notch signalling and haematopoietic stem cell formation during embryogenesis. Journal of Cellular Physiology 222, (1) (01): 11-6.
Gersh, Bernard J., Robert D. Simari, Atta Behfar, Carmen M. Terzic, and Andre Terzic. 2009. Cardiac cell repair therapy: A clinical perspective. Mayo Clinic Proceedings.Mayo Clinic 84, (10) (10): 876-92.
Gonzales, Christine, and Thierry Pedrazzini. 2009. Progenitor cell therapy for heart disease. Experimental Cell Research 315, (18) (11/01): 3077-85.
Henriksson, Helena, Maria Thornemo, Camilla Karlsson, Olle Hägg, Katarina Junevik, Anders Lindahl, and Helena Brisby. 2009. Identification of cell proliferation zones, progenitor cells and a potential stem cell niche in the intervertebral disc region: A study in four species. Spine 34, (21) (10/01): 2278-87.
Hristov, Mihail, Alma Zernecke, Andreas Schober, and Christian Weber. 2008. Adult progenitor cells in vascular remodeling during atherosclerosis. Biological Chemistry 389, (7) (07): 837-44.
Ikoma, Tomomi, Satoru Kyo, Yoshiko Maida, Satoru Ozaki, Masahiro Takakura, Shinji Nakao, and Masaki Inoue. 2009. Bone marrow-derived cells from male donors can compose endometrial glands in female transplant recipients. American Journal of Obstetrics and Gynecology 201, (6) (12): 608.e1,608.e8.
Jessberger, Sebastian, Fred H. Gage, Amelia J. Eisch, and Diane C. Lagace. 2009. Making a neuron: Cdk5 in embryonic and adult neurogenesis. Trends in Neurosciences 32, (11) (11): 575-82.
Kaiser, Jocelyn. 2009. Stem cells. CIRM awards seek to move cell therapies to the clinic. Science (New York, N.Y.) 326, (5954) (11/06): 780-1.
Kuhn, Nastaran Z., and Rocky S. Tuan. 2010. Regulation of stemness and stem cell niche of mesenchymal stem cells: Implications in tumorigenesis and metastasis. Journal of Cellular Physiology 222, (2) (02): 268-77.
Laflamme, Michael A, Kent Y Chen, Anna V Naumova, Veronica Muskheli, James A Fugate, Sarah K Dupras, Hans Reinecke, et al. 2007. "Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts." Nature Biotechnology 25, (9) : 1015-1024.
Leor, Jonathan, Sharon Gerecht, Smadar Cohen, Liron Miller, Radka Holbova, Anna Ziskind, Michal Shachar, Micha S Feinberg, Esther Guetta, and Joseph Itskovitz-Eldor. 2007. "Human embryonic stem cell transplantation to repair the infarcted myocardium." Heart 93 (10) : 1278-1284.
Li, Liheng and Hans Clevers. 2010. Coexistence of quiescent and active adult stem cells in mammals. Science 327: 542-545.
Liedtke, Stefanie, Milaid Stephan, and Gesine Kögler. 2008. Oct4 expression revisited: Potential pitfalls for data misinterpretation in stem cell research. Biological Chemistry 389, (7) (07): 845-50.
Lu, Janice, Tina Fan, Qiang Zhao, Wei Zeng, Eva Zaslavsky, John J. Chen, Michael A. Frohman, Marc G. Golightly, Stefan Madajewicz, and Wen-Tien Chen. 2010. Isolation of circulating epithelial and tumor progenitor cells with an invasive phenotype from breast cancer patients. International Journal of Cancer.126, (3): 669-83.
Marhaba, Rachid, Pamela Klingbeil, Tobias Nuebel, Irina Nazarenko, Markus W. Buechler, and Margot Zoeller. 2008. CD44 and EpCAM: Cancer-initiating cell markers. Current Molecular Medicine 8, (8) (12): 784-804.
McCall, Michael D., Christian Toso, Emmanuel E. Baetge, and A. M. J. Shapiro. 2010. Are stem cells a cure for diabetes? Clinical Science (London, England: 1979) 118, (2) (01): 87-97.
Metzger, Marco, Petra M. Bareiss, Timm Danker, Silvia Wagner, Joerg Hennenlotter, Elke Guenther, Florian Obermayr, et al. 2009. Expansion and differentiation of neural progenitors derived from the human adult enteric nervous system. Gastroenterology 137, (6) (12): 2063,2073.e4.
Passier, Robert, Linda van Laake W., and Christine L. Mummery. 2008. Stem-cell-based therapy and lessons from the heart. Nature 453, (7193) (05/15): 322-9.
Pekovic, Vanja, and Christopher J. Hutchison. 2008. Adult stem cell maintenance and tissue regeneration in the ageing context: The role for A-type lamins as intrinsic modulators of ageing in adult stem cells and their niches. Journal of Anatomy 213, (1) (07): 5-25.
Polak, Dame Julia M. 2009. Regenerative medicine: A primer for paediatricians. Early Human Development 85, (11) (11): 685-9.
Rittié, Laure, Stefan W. Stoll, Sewon Kang, John J. Voorhees, and Gary J. Fisher. 2009. Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin. Aging Cell 8, (6) 738-51.
Sadri-Ardekani, Hooman, Sefika C. Mizrak, Saskia van Daalen K.M., Cindy M. Korver, Hermien Roepers-Gajadien, Morteza Koruji, Suzanne Hovingh, et al. 2009. Propagation of human spermatogonial stem cells in vitro. JAMA: The Journal of the American Medical Association 302, (19) (11/18): 2127-34.
Salewski, Ryan P. F., Eftekhar Eftekharpour, and Michael G. Fehlings. 2010. Are induced pluripotent stem cells the future of cell-based regenerative therapies for spinal cord injury? Journal of Cellular Physiology 222, (3) 515-21.
Sandy, Ashley R., and Ivan Maillard. 2009. Notch signaling in the hematopoietic system. Expert Opinion on Biological Therapy 9, (11) 1383-98.
Scharfmann, R., B. Duvillie, V. Stetsyuk, M. Attali, G. Filhoulaud, and G. Guillemain. 2008. Beta-cell development: The role of intercellular signals. Diabetes, Obesity & Metabolism 10 Suppl 4, (11): 195-200.
Schöler, Hans,R. 2008. Commentary: Highlight on stem cell research. Biological Chemistry 389, (7) (07): 789-.
Taupin, Philippe. 2009. Adult neurogenesis, neural stem cells and Alzheimer's disease: Developments, limitations, problems and promises. Current Alzheimer Research 6, (12): 461-70.
Tenzen, Toyoaki, Filip Zembowicz, and Chad A. Cowan. 2010. Genome modification in human embryonic stem cells. Journal of Cellular Physiology 222, (2) (02): 278-81.
Sharma, Shikhar, Theresa K. Kelly, and Peter A. Jones. 2010. Epigenetics in cancer. Carcinogenesis 31, (1) 27-36.
Tenzen, Toyoaki, Filip Zembowicz, and Chad A. Cowan. 2010. Genome modification in human embryonic stem cells. Journal of Cellular Physiology 222, (2) 278-81.
The players might either download the computer software program and play or head over to the sites directly. Remember if you want to have any money, then you want to deposit money in your account once you write one. Three and even five reel slots are also a big strike with players. best ipad keyboard case mini Ipad Covers iphone 5 Accessories (http://grizzlygadgets.com/) best ipad 2 case new ipad cases ipad 3 cases with keyboard - http://grizzlygadgets.com/ - Best Ipad Mini Case waterproof iphone case best galaxy s3 accessories ipad 2 leather case best Iphone 4 Case galaxy s2 accessories (grizzlygadgets.com) best ipad 4 cases best iphone Case (Grizzlygadgets.com) iphone charger best ipad case (Http://grizzlygadgets.com/best-ipad-case?7195) iphone 5 screen protector s3 case iphone 5 wallet case iphone 4 covers lifeproof iphone case best iphone 4 cases iphone 5 lifeproof case (http://grizzlygadgets.com/iphone-5-case?14224) best iphone 4 case best iphone 4s cases best iphone 4s cases best iphone 5 cases cases for ipad 87 coolest iphone cases samsung galaxy s3 cases best ipad case best iphone 4s cases Iphone 5 Battery Case mini ipad covers leather iphone 5 case ipad mini keyboard iphone 4 covers waterproof iphone case ipad mini cases ipad 3 case cases for the samsung galaxy s74 ipad case with keyboard Apple Ipad Accessories best iphone cases iphone 5 bumper case iphone 5 leather case ipad mini cover best iphone case ipad accessories accessories for samsung galaxy s16 iphone 4S accessories ipad cover (grizzlygadgets.com) ipad covers unique iphone 4 cases iphone 5 case iphone 4s cases ipad bluetooth keyboard ipad mini keyboard case, http://grizzlygadgets.com/ipad-keyboard-cases?5222, ipad Mini cases ipad case with keyboard (grizzlygadgets.com) best iphone Case best iphone Case Iphone 5 accessories best case for iphone 109 iphone 4 case kate spade iphone 4 case Best iphone 4 case galaxy s3 waterproof case [grizzlygadgets.com] ipad 4 cases ipad mini case best case for iphone 5 best case for iphone 5 best ipad 3 cases iphone 5 accessories Ipad 2 Case Speck iphone 5 case Custom galaxy s3 case ipad stand (grizzlygadgets.com) samsung galaxy s2 cases ipad accessories iphone 4s accessories ipad mini keyboard custom ipad 3 cases iphone 4 cases Iphone 4 Wallet case iphone accessories best iphone 4 case Ipad mini Case leather cases for iphone 122 - grizzlygadgets.com - samsung galaxy s3 case (grizzlygadgets.com) ipad accessories iphone 5 wallet case ipad mini cases ipad 3 keyboard iphone 5 covers iphone 5 cover (grizzlygadgets.com) Ipad 3 Cases iphone 5 headphones phone cases for galaxy s6 samsung galaxy S3 cases best iphone 4 cases - Darlene, best iphone cases leather iphone cases; http://grizzlygadgets.com/, samsung s3 cases Ipad mini covers leather iphone cases (grizzlygadgets.com) cool iphone 4s cases
Posted by: mini ipad covers | October 04, 2013 at 09:23 AM
Both products of the casino products are also free because of viruses, spyware or extra malware. A player need only to participate in for an account with receive $15 deposited towards their account. The device lies in melding our cards faster than my opponents. i pad covers case for ipad 121 best ipad case ipad 2 cases and covers targus ipad case ipad mini cover - grizzlygadgets.com - best case for galaxy s67 best case for iphone 5 new ipad cases (Imogene) iphone 5 accessories (grizzlygadgets.com) leather iphone 4 case (grizzlygadgets.com) best iphone 5 accessories best Iphone 5 Cases samsung galaxy s2 accessories samsung s3 case - grizzlygadgets.com, Galaxy S2 Phone Case (Grizzlygadgets.Com) iphone 5 covers best ipad 3 case iphone cover best iphone 5 accessories unique iphone 4s cases best ipad cover (grizzlygadgets.com) iphone 5 accessories (grizzlygadgets.com) ipad smart cover lifeproof iphone 4s case waterproof iphone 4 case best galaxy s3 cases iphone accessories cool Iphone 4S cases leather ipad 3 case Samsung galaxy s3 Accessories ipad 2 leather case (grizzlygadgets.com) ipad 4 cases ipad mini covers (grizzlygadgets.com) ipad 2 cases iphone 4s accessories best ipad keyboard; grizzlygadgets.com, samsung Galaxy s3 cases Amazon iphone 4s case (grizzlygadgets.com) ipad 3 cases with keyboard cute iphone 5 cases (grizzlygadgets.com) samsung galaxy s2 cases best iphone 4 cases cool ipad accessories iphone 5 cases; Imogene, iphone 5 lifeproof case Iphone 4S cases best ipad keyboard iphone 5 bumper case cute Iphone 5 cases ipad smart cover best iphone cases Iphone 4S Case leather iphone case Ipad cover with Keyboard galaxy s3 waterproof Case (grizzlygadgets.com) cool ipad accessories Samsung galaxy S2 case iphone 5 cases ipad 2 covers and cases (grizzlygadgets.com) iphone 5 case iphone 5 cases mini ipad cases (http://grizzlygadgets.com) iphone 4 case ipad keyboard case apple ipad accessories ipad cases speck iphone 5 case best keyboard for ipad apple ipad 2 case (http://grizzlygadgets.com) phone cases for iphone 63 iphone 4 accessories ipad 3 covers cheap iphone 5 cases apple ipad 2 case coolest iphone 5 cases mini ipad cases cases for ipad 76 s3 case best iphone 5 cases iphone 5 case keyboard for ipad iphone 5 cases unique iphone 4s case ipad 3 cases with keyboard iphone 4 cases phone cases for galaxy s107 cheap iphone 4 cases ipad 4 case iphone 5 accessories (Imogene) best iphone 5 cases (http://grizzlygadgets.com/) case For Samsung galaxy S117 (grizzlygadgets.Com) best ipad mini case best iphone Cases ipad 2 cases and covers galaxy s3 phone cases case for ipad 53 (grizzlygadgets.com) ipad cases (grizzlygadgets.com) coolest iphone 4 cases metal iphone case Best Iphone 4 Case best ipad 3 case coolest iphone 4 cases galaxy s3 accessories (http://grizzlygadgets.com) ipad mini covers best iphone 5 cases ipad case with keyboard
Posted by: i pad covers | October 04, 2013 at 08:08 AM
All you should do is match your hands with the Dealer's to the top level card and take their suggested action. This is why it is very important take this game to a great extent even if you doesn't deposit any money from the very first. The tables come in a range of shapes as well. best ipad accessories iphone accessories aluminum iphone 5 case ipad 3 cases with keyboard (http://grizzlygadgets.com/) samsung galaxy s2 case (http://grizzlygadgets.com/samsung-galaxy-s2-case) cool iphone 4 cases speck iphone 4 case Ipad 2 cases best ipad 4 cases iphone 5 cover samsung galaxy s2 accessories Best Ipad 3 Case ipad 2 leather case case for galaxy s3 iphone 4s cases best ipad 3 cases case for samsung galaxy s2 (http://grizzlygadgets.com/) iphone 5 headphones Ipad Keyboard Case leather ipad 2 case (grizzlygadgets.com) Iphone 5 Accessories case for samsung galaxy s3 cases for samsung galaxy s2 aluminum iphone 5 case galaxy s2 phone cases (http://grizzlygadgets.com/samsung-galaxy-s2-case) best keyboard for Ipad galaxy s3 case otterbox Iphone 4 Cases iphone 5 cases cool ipad 2 cases iphone 4 battery cases For galaxy s2, Grizzlygadgets.com, aluminum iphone 4 case lifeproof case for galaxy s3 Best iphone 4 cases iphone case ipad 3 Cases And covers iphone 5 case [grizzlygadgets.com] iphone 5 Lifeproof case (http://grizzlygadgets.Com/iphone-5-case) Galaxy S2 accessories; grizzlygadgets.com, galaxy s3 charging case best ipad cases iphone 4s cases iphone 5 accessories iphone 5 adapter (http://grizzlygadgets.com/iphone-5-accessory) Best Ipad Keyboard Case - Http://Grizzlygadgets.Com - ipad 3 cases with keyboard metal iphone 5 cases samsung galaxy s3 cases ipad mini cases best ipad mini cases (http://grizzlygadgets.com/) Ipad 3 accessories waterproof iphone case ipad charger cases for ipad 2 leather cases for iphone 5 cheap iphone 5 cases iphone 5 cable [grizzlygadgets.com] best samsung galaxy s3 case cool ipad accessories iphone 4s case ipad 2 cases and covers lifeproof case for galaxy s3 galaxy s2 phone cases lifeproof case for galaxy s3 leather case for iphone 5 ipad 2 cases targus ipad 3 case best iphone case phone cases for galaxy s2 (grizzlygadgets.com) ipad case with keyboard ipad bluetooth keyboard cool iphone case ipad 3 cover iphone 5 adapter (grizzlygadgets.Com) leather cases for iphone 5 iphone 5 bumper case apple iphone accessories iphone accessories coolest iphone 4 cases iphone 5 leather case best iphone 4 case accessories for samsung galaxy s3 ipad Mini case best iphone 4s case iphone case keyboard for ipad best case for samsung galaxy s3 iphone 4s accessories Samsung Galaxy S3 Cases phone cases for galaxy s3; grizzlygadgets.com, iphone 4 aluminum case best iphone 4s cases leather iphone case best ipad mini case iphone 4 accessories best case for galaxy s3 keyboard for ipad best ipad cover iphone cases ipad 2 covers ipad mini keyboard iphone accessories (grizzlygadgets.com) Apple ipad 2 Case new ipad case iphone 4 cases best iphone 4 case (http://grizzlygadgets.com/iphone-4-4s-accessory)
Posted by: best ipad accessories | October 02, 2013 at 06:28 AM
Stem Cell Therapy Clinics although experimental is proving to be an incredible tool and one that will be getting alot more press in the months ahead. What is this "hush-hush" procedure? Stem Cell therapy! No - not using someone else's stem cells, YOUR OWN! That's right - and it sounds fascinating.
Posted by: Stem Cell Therapy Clinics | May 10, 2010 at 04:51 AM